Ferinject IV Injection or Infusion 500mg/10ml

Uses of Ferinject IV Injection or Infusion 500mg/10ml

Treatment of iron deficiency anemia.

How does Ferinject IV Injection or Infusion 500mg/10ml work?

Replenishes iron stores in the body, vital for forming new red blood cells and hemoglobin.

Side Effects of Ferinject IV Injection or Infusion 500mg/10ml

Common side effects include nausea, hypertension, flushing, decreased blood phosphorus, dizziness, vomiting, pruritus, rash, urticaria, wheezing, injection site discoloration, headache, increased alanine aminotransferase, dysgeusia, hypotension, constipation, and serious anaphylactic/anaphylactoid reactions.

Quick Suggestions:

• Ferinject 500 is used when oral iron fails.
• Injection may cause allergic reactions; observe for 30 minutes after each dose.
• Regularly monitor blood pressure and iron levels.
• Inform your doctor of any oral iron supplements.
• Avoid alcohol consumption during treatment.
• Stool discoloration is normal.
• Hypersensitivity and hypertension may occur; monitor accordingly.

Indication of Ferinject IV Injection or Infusion 500mg/10ml

Ferric Carboxymaltose is prescribed for treating iron deficiency anemia in adult patients who:

• Cannot tolerate oral iron or have had an inadequate response to it.
• Have non-dialysis dependent chronic kidney disease.

Tips:

• For patients weighing 50 kg or more: Administer Ferric Carboxymaltose in two doses spaced at least 7 days apart, with each dose being 750 mg, not exceeding a total cumulative dose of 1500 mg of iron per course.
• For patients weighing less than 50 kg: Administer Ferric Carboxymaltose in two doses spaced at least 7 days apart, with each dose being 15 mg/kg body weight, not exceeding a total cumulative dose of 1500 mg of iron per course.
• Ferric carboxymaltose is given intravenously either as a slow push or by infusion. For infusion, dilute up to 750 mg of iron in 250 mL of sterile 0.9% sodium chloride injection, ensuring a concentration of at least 2 mg of iron per mL, and administer over 15 minutes.
• The solution is stable for 72 hours when stored at room temperature after being added to an infusion bag.

Dosage of Ferinject IV Injection or Infusion 500mg/10ml

Dose: Adults: 750 mg IV once, followed by a second dose 7 days later; dosage adjustment for weight may be necessary.

Administration of Ferinject IV Injection or Infusion 500mg/10ml

Given intravenously (IV) by infusion or injection.

Interaction

No formal drug interaction studies have been conducted with Ferinject.

Contraindications

Hypersensitivity to any component.

Pregnancy & Lactation

• Ferric Carboxymaltose falls under Pregnancy Category C, with animal studies showing adverse effects on the fetus. Use in pregnant women may be considered if the potential benefits outweigh the risks.
• Caution is advised during breastfeeding due to limited data on its safety.

Precautions & Warnings

• Monitor patients for signs of hypersensitivity, including anaphylactic reactions, during and after administration.
• Watch for transient elevations in systolic blood pressure, which may occur immediately after dosing.
• Ferric Carboxymaltose belongs to the therapeutic class of Parenteral Iron Preparations.

Storage Conditions:

Store Ferric Carboxymaltose below 30°C and avoid freezing.